Hard-to-heal wounds
Infection and Biofilm Management
In the battle against hard-to-heal wounds, there is an invisible enemy, Biofilm.
MORE THAN SILVER™ technology
A major barrier to wound healing, biofilm is present in at least 78% of hard-to-heal wounds. 1
Thanks to our breakthrough MORE THAN SILVER™ technology - which contains ionic silver together with a surfactant and a metal chelating agent - our dressing delivers superior2 antibiofilm performance compared to other tested silver dressings.
A Multinational Randomised Controlled Trial3
Effectiveness of an enhanced silver-containing dressing in hard-to-heal venous leg ulcers: a randomised controlled trial3
Evidence shows Aquacel Ag+ Extra™ effectively disrupts and destroys biofilm4,5 with Aquacel® Ag+ Extra™ achieving superior complete wound closure vs DACC dressings in an RCT.3
A Health Economic Publication6
Management of VLUs with Aquacel® Ag+Extra™ versus Cutimed® Sorbact® was associated with
✓ Higher rate of and shorter time to complete wound closure.
✓ Reduction in the total cost of leg ulcer management.
✓ Improvement in HRQoL.
NICE-published cost comparison
The NICE Late Stage Assessment includes a health economic analysis of infected leg ulcers using different types of antimicrobial agents. NICE reviewed cost-modelling shows Aquacel® Ag+ Extra™ saves >£500 per patient to treat an infected leg ulcer.⁷
Our Infection and Biofilm Management Product Portfolio
Aquacel® Ag+ Extra™
AQUACEL® Ag Foam
AQUACEL® Ag Burn Hydrofiber® Dressing, Sterile
AQUACEL® Ag SURGICAL cover dressing
Not all claims are supported in all regulatory geographies.
1. Malone M et al. 2017. The prevalence of biofilm in chronic wounds: a systematic review and meta-analysis of published data. JWC: 20-25.
2. Bowler PG, Parsons D. Combatting wound biofilm and recalcitrance with a novel anti-biofilm Hydrofiber® wound dressing. Wound Medicine 14 (2016) 6-11.
3. Beraldo S. et al. Effectiveness of an enhanced silver-containing dressing in hard-to-heal venous leg ulcers: a randomised controlled trial. Journal of Wound Care, 2025.
4. Meredith K, et al. Assessment of the Antibiofilm Performance of Silver-Containing Wound Dressings: A Dual-Species Biofilm Model. Cureus. 2024; 16(9):e70086.
5. Meredith et al. Assessment of Silver-Containing Gelling Fiber Dressings Against Antibiotic-Resistant Pathogens Using an in vitro Biofilm Model. Infect Drug Resist. 2023 Nov 2;16:7015-7019.
6. Guest, J. F. (2025). Cost-effectiveness of an enhanced silver-containing dressing in treating hard-to-heal venous leg ulcers. JWC. 34, 1-11.
AP-76093-GBL-ENG